Richard Beigi, MD, MSc

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Richard Beigi, MD, MSc

Professor, Reproductive Sciences, Department of Obstetrics, Gynecology & Reproductive Sciences President, UPMC Magee-Womens Hospital

Contact

UPMC Magee-Womens Hospital
300 Halket Street
Pittsburgh, PA 15213

Phone: 412-641-3313
Email: beigrh@upmc.edu

Administrative Contact
Stacy Dean
Email: sdean@upmc.edu

Area of Research

Infectious Diseases

Pregnant & lactating women have traditionally not been included in clinical trials, we are working to change this paradigm in an ethically and scientifically responsible manner.
Richard Beigi, MD, MSc

Research in Brief

Dr. Beigi primarily performs clinical trials related to testing of various infectious disease related pharmaceutical products for the prevention and management of ID conditions in pregnant and lactating women. He is a member of the University of Pittsburgh’s Division of Reproductive Infectious Diseases and Immunology and an investigator in the Microbicides Trials Network.

Current Projects

Trial to Evaluate Safety & Immunogenicity of MENVEO Conjugate Vaccine in Pregnant Women – VTEU/NIH/NIAID

Pharmacokinetics of the Dapivirine Vaginal Ring in Lactating Women – MTN/NIH/NIAID

Learn more.

Selected Publications

Pillai VC, Han K, Beigi RH, Hankins GD, Clark S, Hebert MF, Easterling TR, Zajicek A, Ren Z, Caritis SN, Venkataramanan V. Population pharmacokinetics of oseltamivir in non-pregnant and pregnant women. Br J Clin Pharmacol 2015;80:1042-50.
Beigi RH, Pillai VC, Venkataramanan R, Caritis SN. Oseltamivir for the Treatment of H1N1 Influenza During Pregnancy. Clin Pharmacol Ther 2015;98:403-5.
Beigi RH, Fortner KB, Munoz FM, Roberts J, Gordon JL, Han HH, Glenn G, Dormitzer PR, Gu XX, Read JS, Edwards K, Patel SM, Swamy GK. Maternal Immunization: Opportunities for Scientific Advancement. Clin Infect Dis 2014;59 Suppl 7:S408-14.
Beigi RH, Noguchi L, Parsons T, Macio I, Kunjara Na Ayudhya R, Chen J, Hendrix C, Masse B, Valentine M, Piper J, Watts H. Pharmacokinetics and placental transfer of single dose tenofovir 1% vaginal gel in term pregnancy. J Infect Dis 2011;204:1527-31.
Omer SD, Beigi RH. Pregnancy in the Time of Zika: Addressing barriers for developing vaccines and other countermeasures for pregnant women. JAMA 2016 Mar 22-29;315(12):1227-8. doi: 10.1001/jama.2016.2237. PMID: 26914692.
Adibi JJ, Cartus A, Marquez Jr ETA, Beigi RH. Teratogenic effects of the Zika virus and the role of the placenta. Lancet 2016 Mar 4. pii: S0140-6736(16)00650-4. doi: 10.1016/S0140-6736(16)00650-4. PMID: 26952548.
Noguchi L, Montgomery E, Biggio J, Hendrix C, Bogen D, Hillier SS, Dai J, Piper J, Marzinke M, Dezzutti C, Isaacs K, Schwartz J, Watts DH, Beigi RH. Detectable tenofovir levels in breastfeeding infants of mothers exposed to topical tenofovir. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5616-9. doi: 10.1128/AAC.00645-16. Print 2016 Sep. PMID: 27401570.
Beigi RH, Noguchi LM, Montgomery E, Biggio J, Hendrix CW, Marzinke M, Dai JY, Pan J, Kunjara P, Schwartz J, Isaacs K, Piper JM, Watts DH. A randomized safety and pharmacokinetic trial of daily tenofovir 1% gel in term and near-term pregnancy. J Int AIDS Soc. 2016 Sep 21;19(1):20990. doi: 10.7448/IAS.19.1.20990. PMID: 27658440.
Beigi RH. Emerging infectious diseases in pregnancy. Obstet Gynecol. 2017 May;129(5):896-906. doi: 10.1097/AOG.0000000000001978. PMID: 28383378
Noguchi L, Hoesley C, Kelly C, Scheckter R, Bunge K, Nel A, Marzinke M, Hendrix C, Dezzutti C, Hillier S, Bogen D, Piper J, Beigi R. Pharmacokinetics of Dapivirine Transfer into Blood Plasma, Breast Milk, and Cervicovaginal Fluid of Lactating Women using the Dapivirine Vaginal Ring. Antimicrob Agents Chemother. 2019 Jan 2. pii: AAC.01930-18. doi: 10.1128/AAC.01930-18. PMID: 30602513.

For additional publications, visit Pubmed.