Assistant Professor, Department of Surgery, Division of Surgical Oncology, Section of Breast Diseases
Dr McAuliffe’s research objective is to improve our understanding of pre-invasive breast neoplasms including DCIS (ductal carcinoma in situ) and LCIS (lobular carcinoma in situ) with the over-arching goal of halting the development of invasive ductal or lobular breast cancer. Specifically, her group studies two related themes. The first examines the interplay between the body’s immune system and growth of breast ductal or lobular cells. The second involves the role of cellular survival mechanisms, such as autophagy, in the progression from in situ to invasive breast cancer. Building on her training in molecular genetics, her team’s translational studies utilize tissue cell culture, murine models and clinical specimens from retrospective evaluations and clinical trials.