Reproductive Endocrinology and Fertility research focuses on the areas of:

  • ovarian biology
  • hypothalamic-pituitary-gonadal axis
  • female and male germ cell development
  • infertility and restoration of fertility

Magee-Womens Research Institute researchers interrogate the fundamental physiological mechanisms that govern germ cell biology and reproduction in mammalian species, and examine pathways that lead to human infertility. Emphasis is placed on hypothalamic, pituitary, and gonadal endocrinology that impacts ovulation, fertilization, implantation, and relevant diseases across the reproductive life cycle, such as premature ovarian failure and polycystic ovary syndrome.

In-depth research spans functional genetic characterization of germline stem cells, and germ cell development into mature eggs and sperms. These studies are based on cutting-edge genetic models that shed light on infertility, transgenesis, and unique methods for restoration of fertility.