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- Gerald P. Schatten, PhD
Gerald P. Schatten, PhD
Professor, Department of Obstetrics, Gynecology & Reproductive Sciences; Professor, Department of Cell Biology & Bioengineering; Director, Division of Developmental & Regenerative Medicine, University of Pittsburgh
Understanding fertilization is essential for diagnosing and treating infertility, and for contraceptive optimizations. By exploring defects in gametes, our discoveries are improving Assisted Reproduction Technologies.
Gerald P. Schatten, PhD
Research in Brief
Dr. Schatten's research focuses on understanding the fundamental processes of fertilization and early development. By studying the cellular and molecular mechanisms involved, his work aims to improve assisted reproductive technologies and contribute to advancements in regenerative medicine.
Current Projects
- Co-Founder and director of Frontiers in Human Embryonic Stem Cell Research (FrHESC), an intensive laboratory and lecture-based introduction to this emerging research field.
- Director of Frontiers in Alzheimer’s and Aging Research Experiences
- Director of Frontiers in Emerging, Reemerging and Zoonotic Diseases
- Director of Forefronts in Substance Abuse Disorders during Pregnancy, Postpartum, and Pediatrics
Selected Publications
- Schatten, G., Simerly, C., Manil-Ségalen, M., Castro, C., Redinger, C., Kong, D., Verlhac, M.-H., Loncarek, J. Separation and Loss of Centrioles from Primordial Germ Cells to Mature Oocytes in the Mouse. Scientific Reports. 2018.
- Fishman, E.L., Jo, K., Nguyen, Q.P.H., Kong, D., Royfman, R., Cekic, A.R., Khanal, S., Miller, A.L., Simerly, C., Schatten, G., Loncarek, J., Mennella, V., Avidor-Reiss, T. A Novel Atypical Sperm Centriole is Functional During Human Fertilization. Nature Communications. 2018.
- Schatten, G., Stearns, T. Sperm Centrosomes: Kiss Your Asterless Goodbye, for Fertility’s Sake. Current Biology. 2015.
- Schatten, G., Simerly, C. LEGOs® and Legacies of Centrioles and Centrosomes. EMBO Reports. 2015.
- Hewitson, L., Dominko, T., Takahashi, D., Ramalho-Santos, J., Sutovsky, P., Fanton, J., Jacob, D., Monteith, D., Neuringe, M., Battaglia, D., Simerly, C., Schatten, G. Births of ICSI Monkeys: Unique Checkpoints During the First Cell Cycle of Fertilization. Nature Medicine. 1999.
For a complete list of publications, click here.
Research Group
Calvin Simerly, PhD
Angela Palermo, BA
Carrie J. Hartnett, MFS