Magee-Womens Research Institute & Foundation

• Modeling protein interactions in meiotic recombination using computational structural tools.
• Studying the regulation of meiotic double-strand break formation and repair mechanisms in C. elegans. 

• Raices M, Balmir F, Silva N, Li W, Grundy MK, Hoffman DK, Altendorfer E, Camacho CJ, Bernstein KA, Colaiácovo MP, Yanowitz JL. Genetic and physical interactions reveal overlapping and distinct contributions to meiotic double-strand break formation in C. elegans. bioRxiv [Preprint]. 2025 Aug 7:2024.02.23.581796. doi: 10.1101/2024.02.23.581796. PMID: 38463951; PMCID: PMC10925144.
• Raices M, Bowman R, Smolikove S, Yanowitz JL. Aging Negatively Impacts DNA Repair and Bivalent Formation in the C. elegans Germ Line. Front Cell Dev Biol. 2021 Aug 4;9:695333. doi: 10.3389/fcell.2021.695333. PMID: 34422819; PMCID: PMC8371636.
• Janisiw E, Raices M, Balmir F, Paulin LF, Baudrimont A, von Haeseler A, Yanowitz JL, Jantsch V, Silva N. Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity. Nat Commun. 2020 Sep 25;11(1):4869. doi: 10.1038/s41467-020-18693-1. PMID: 32978394; PMCID: PMC7519143. 

For additional publication, visit PubMed.